PATH-18. A MULTI-CENTER CASE SERIES OF ADULT K27M MUTATED DIFFUSE MIDLINE GLIOMAS REVEALING A POPULATION UNIQUE FROM PAEDIATRIC CASES

BACKGROUND: Histone mutations in the K27M gene were first described in 2014, and incorporated into the WHO CNS tumour classification system in 2016. They are typically associated with diffuse midline gliomas (DMG). Presenting symptoms vary greatly, with some experiencing significant delay in diagnos...

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Publicat a:Neuro Oncol
Autors principals: Yuile, Alexander, De Silva, Madhawa, Kastelan, Marina, Cheung, Veronica, Sy, Joanne, Buckland, Michael, Drummond, Jamie, Back, Michael, Wheeler, Helen
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
Matèries:
Molecular Pathology & Classification
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651517/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.700
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