PATH-18. A MULTI-CENTER CASE SERIES OF ADULT K27M MUTATED DIFFUSE MIDLINE GLIOMAS REVEALING A POPULATION UNIQUE FROM PAEDIATRIC CASES

BACKGROUND: Histone mutations in the K27M gene were first described in 2014, and incorporated into the WHO CNS tumour classification system in 2016. They are typically associated with diffuse midline gliomas (DMG). Presenting symptoms vary greatly, with some experiencing significant delay in diagnos...

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Publicado en:Neuro Oncol
Autores principales: Yuile, Alexander, De Silva, Madhawa, Kastelan, Marina, Cheung, Veronica, Sy, Joanne, Buckland, Michael, Drummond, Jamie, Back, Michael, Wheeler, Helen
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2020
Materias:
Molecular Pathology & Classification
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651517/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.700
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