TMOD-34. PATIENT-DERIVED XENOGRAFT AND CELL LINE MODELS FACILITATE NOVEL TREATMENT DISCOVERY IN CENTRAL NERVOUS SYSTEM LYMPHOMAS

Lymphomas of the central nervous system (CNSL) are rare tumors with few treatment options; however, recent genomic studies have uncovered several druggable targets. To facilitate novel treatment discovery, we sought to establish patient-derived xenograft (PDX) models and cell lines from patients wit...

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Dettagli Bibliografici
Pubblicato in:Neuro Oncol
Autori principali: Meredith, David, Chow, Kin Hoe, Kao, Pei-Lun, Zeng, Yu, Sinha, Rileen, Shetty, Aniket, Tolstorukov, Michael, Tran, Tony, Yerrum, Smitha, Chukwueke, Ugonma, Bi, Wenya Linda, Arnaout, Omar, Smith, Timothy, Ligon, Keith, Nayak, Lakshmi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2020
Soggetti:
Tumor Models
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651474/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.984
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