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46. PAN-CANCER ANALYSIS OF ORTHOTOPIC PATIENT DERIVED XENOGRAFTS FROM BRAIN METASTASES

Brain metastases (BM) are a leading cause of cancer death and prognosis remains poor despite treatment advances at other sites. Models are central to therapeutic development, but few orthotopic patient-derived xenograft (PDX) models of BM exist. To represent diversity across BM types, we established...

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Pubblicato in:Neurooncol Adv
Autori principali: Zeng, Yu, Pelton, Kristine, Yerrum, Smitha, Kao, Pei-Lun, Sinai, Claire, Tran, Tony, Sinha, Rileen, Shetty, Aniket, Tolstorukov, Michael Y, Jaber, Aliya, Freitas, Dylan E, Pisano, William, Verselis, Sigitas J, Herbert, Zach T, Lin, Nancy U, Zhao, Jean J, Weinstock, David M, Chukwueke, Ugonma N, Aizer, Ayal A, Chiocca, E Antonio, Bi, Wenya Linda, Wen, Patrick Y, Lee, Eudocia Q, Nayak, Lakshmi, Meredith, David M, Santagata, Sandro, Chow, Kin-Hoe, Ligon, Keith L
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7401414/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdaa073.034
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