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STEM-20. A CANCER STEM CELL-SELECTIVE APOPTOSIS-INDUCING SMALL MOLECULE FOR THE TREATMENT OF GBM

INTRODUCTION: Glioblastoma multiforme (GBM) is the most aggressive form of primary brain cancer. A subpopulation of multipotent cells termed GBM cancer stem cells (CSCs) play a critical role in tumor initiation and maintenance, drug resistance, and recurrence following surgery. New therapeutic strat...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Skirboll, Stephen, Lucki, Natasha, Villa, Genaro, Vergani, Naja, Bollong, Michael, Beyer, Brittney, Lee, Jae Wook, Anglin, Justin, Spangenberg, Stephan, Chin, Emily, Sharma, Amandeep, Johnson, Kevin, Sander, Phillipp, Gordon, Perry, Wurdak, Heiko, Schultz, Peter, Mischel, Paul, Lairson, Luke
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651318/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.837
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