Small molecule-mediated inhibition of myofibroblast transdifferentiation for the treatment of fibrosis

Fibrosis, a disease in which excessive amounts of connective tissue accumulate in response to physical damage and/or inflammatory insult, affects nearly every tissue in the body and can progress to a state of organ malfunction and death. A hallmark of fibrotic disease is the excessive accumulation o...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Bollong, Michael J., Yang, Baiyuan, Vergani, Naja, Beyer, Brittney A., Chin, Emily N., Zambaldo, Claudio, Wang, Danling, Chatterjee, Arnab K., Lairson, Luke L., Schultz, Peter G.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2017
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5422806/
https://ncbi.nlm.nih.gov/pubmed/28416697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1702750114
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