IMMU-42. DUAL ACTIVATION OF THE cGAS-STING PATHWAY AND AIM2-INDUCED PYROPTOSIS BY TUMOR-TREATING FIELDS PRODUCES ANTI-TUMOR IMMUNITY IN GLIOBLASTOMA

OBJECTIVES: Tumor Treating Fields (TTFields) was approved in combination with adjuvant temozolomide chemotherapy for newly diagnosed Glioblastoma (GBM) patients and resulted in a significant improvement in overall survival. TTFields are low-intensity alternating electric fields that are thought to d...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Chen, Dongjiang, Sebastian, Mathew, Hutchinson, Tarun, Ghiaseddin, Ashley, Warren, Sonisha, Allen, Annie, Jin, Dan, Le, Son, Tran, David
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651242/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.472
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