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IMMU-06. TTFIELDS INDUCES IMMUNOGENIC CELL DEATH AND STING PATHWAY ACTIVATION THROUGH CYTOPLASMIC DOUBLE-STRANDED DNA IN GLIOBLASTOMA CELLS

OBJECTIVES: Glioblastoma (GBM) is the most common and deadliest malignant brain cancer in adults. Tumor Treating Fields (TTFields) was approved in combination with adjuvant temozolomide chemotherapy for newly diagnosed GBM patients. The addition of TTFields resulted in a significant improvement in o...

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Foilsithe in:Neuro Oncol
Main Authors: Chen, Dongjiang, Thomas, Nagheme, Ren, Jie, Le, Son, Sebstian, Mathew, Deng, Changwang, Jin, Dan, Tran, David
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847601/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.500
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