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IMMU-42. TTFIELDS INDUCES IMMUNOGENIC CELL DEATH AND STING PATHWAY ACTIVATION THROUGH CYTOPLASMIC DOUBLE-STRANDED DNA IN GBM

Glioblastoma (GBM) is the most common and deadliest malignant brain cancer in adults despite aggressive chemoradiotherapy. Recently, Tumor Treating Fields (TTFields) were approved in combination with adjuvant temozolomide chemotherapy for newly diagnosed GBM patients. The addition of TTFields result...

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Vydáno v:Neuro Oncol
Hlavní autoři: Chen, Dongjiang, Thomas, Nagheme, Ren, Jie, Le, Son, Deng, Changwang, Jin, Dan, Sebastian, Mathew, Nguyen, Duy, Tran, David
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216405/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.545
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