IMMU-42. TTFIELDS INDUCES IMMUNOGENIC CELL DEATH AND STING PATHWAY ACTIVATION THROUGH CYTOPLASMIC DOUBLE-STRANDED DNA IN GBM

Glioblastoma (GBM) is the most common and deadliest malignant brain cancer in adults despite aggressive chemoradiotherapy. Recently, Tumor Treating Fields (TTFields) were approved in combination with adjuvant temozolomide chemotherapy for newly diagnosed GBM patients. The addition of TTFields result...

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Опубликовано в: :Neuro Oncol
Главные авторы: Chen, Dongjiang, Thomas, Nagheme, Ren, Jie, Le, Son, Deng, Changwang, Jin, Dan, Sebastian, Mathew, Nguyen, Duy, Tran, David
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216405/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.545
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