IMMU-06. TTFIELDS INDUCES IMMUNOGENIC CELL DEATH AND STING PATHWAY ACTIVATION THROUGH CYTOPLASMIC DOUBLE-STRANDED DNA IN GLIOBLASTOMA CELLS

OBJECTIVES: Glioblastoma (GBM) is the most common and deadliest malignant brain cancer in adults. Tumor Treating Fields (TTFields) was approved in combination with adjuvant temozolomide chemotherapy for newly diagnosed GBM patients. The addition of TTFields resulted in a significant improvement in o...

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Dades bibliogràfiques
Publicat a:Neuro Oncol
Autors principals: Chen, Dongjiang, Thomas, Nagheme, Ren, Jie, Le, Son, Sebstian, Mathew, Deng, Changwang, Jin, Dan, Tran, David
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2019
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847601/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.500
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