CSIG-06. PLATELET DERIVED GROWTH FACTOR RECEPTOR ALPHA AS AN ONCOGENIC DRIVER IN GLIOBLASTOMA

Activated platelet derived growth factor receptor alpha (PDGFRα) is essential for the maintenance of oligodendrocyte progenitors. Differential signaling results from phosphorylation of specific tyrosine residues in the kinase insert (KI) domain present in most RTKs in variable length. Our goal is to...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Berezovsky, Artem, Irtenkauf, Susan, Transou, Andrea, Hasselbach, Laura, Mikkelsen, Tom, de Carvalho, Ana
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Cell Signaling and Signaling Pathways
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651131/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.118
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