CSIG-06. PLATELET DERIVED GROWTH FACTOR RECEPTOR ALPHA AS AN ONCOGENIC DRIVER IN GLIOBLASTOMA

Activated platelet derived growth factor receptor alpha (PDGFRα) is essential for the maintenance of oligodendrocyte progenitors. Differential signaling results from phosphorylation of specific tyrosine residues in the kinase insert (KI) domain present in most RTKs in variable length. Our goal is to...

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發表在:Neuro Oncol
Main Authors: Berezovsky, Artem, Irtenkauf, Susan, Transou, Andrea, Hasselbach, Laura, Mikkelsen, Tom, de Carvalho, Ana
格式: Artigo
語言:Inglês
出版: Oxford University Press 2020
主題:
Cell Signaling and Signaling Pathways
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651131/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.118
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