CTNI-76. PHASE 2 CLINICAL TRIAL OF VAL-083 IN NEWLY DIAGNOSED MGMT-UNMETHYLATED GBM

Approximately 60% of glioblastoma multiforme (GBM) patients possess an unmethylated methylguanine DNA-methyltransferase (MGMT) promoter region, which confers a limited response to standard-of-care treatment with temozolomide (TMZ), resulting in shorter median survival when compared to patients with...

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Bibliografiske detaljer
Udgivet i:Neuro Oncol
Main Authors: Chen, Zhong-ping, Guo, Cheng-Cheng, Yang, Qun-ying, Wu, Shao-xiong, Li, Jia-Wei, Bacha, Jeffrey, Johnson, Greg, Langlands, John, Schwartz, Richard, Kwan, Claire, Kanekal, Sarath, Steino, Anne, Lopez, Lorena, Brown, Dennis
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
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Clinical Trials: Non-Immunologic
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651087/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.242
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