ACTR-71. PHASE 1/2 STUDY OF DIANHYDROGALACTITOL (VAL-083) WITH RADIATION THERAPY IN PATIENTS WITH NEWLY DIAGNOSED, MGMT-UNMETHYLATED GLIOBLASTOMA

Glioblastoma (GBM) is the most common and aggressive primary brain cancer. Current standard-of-care includes surgery followed by chemo-radiation and temozolomide. An unmethylated promoter for O6-methylguanine-DNA-methyltransferase (MGMT) is a validated biomarker for temozolomide-resistance and is st...

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Publicado no:Neuro Oncol
Main Authors: Chen, Zhong-ping, Guo, Chengcheng, Bacha, Jeffrey, Steino, Anne, Langlands, John, Kwan, Claire, Kanekal, Sarath, Schwartz, Richard, Lopez, Lorena, Brown, Dennis
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Abstracts
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216509/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.101
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