TAMI-48. ENGRAFTMENT PHENOTYPES IN PRECLINICAL MODEL SYSTEMS REVEAL A FUNCTIONAL SUBGROUP OF PATIENT TUMORS DEPENDENT ON THE BRAIN TUMOR MICROENVIRONMENT FOR GROWTH

The derivation of model systems from patient tumors is a requisite for reproducible and high throughput translational cancer research. However, not all tumors can form a model and those that do often fail to capture the molecular diversity specific to their cancer. The potential tumor-intrinsic unde...

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Veröffentlicht in:Neuro Oncol
Hauptverfasser: Bayley, Nicholas, Tse, Christopher, Zhu, Henan, Yan, Weihong, Gosa, Laura, Baufeld, Lynn, Ta, Lisa, Prins, Robert, Yong, William, Cloughesy, Timothy, Liau, Linda, Graeber, Thomas, Nathanson, David
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2020
Schlagworte:
Tumor Microenvironment/Angiogenesis/Metabolism/Invasion
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7650995/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.935
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