TAMI-06. PRECLINICAL MODELS REVEAL BRAIN-MICROENVIRONMENT SPECIFIC METABOLIC DEPENDENCIES IN GLIOBLASTOMA

Metabolic reprogramming is a hallmark of cancer, and malignant cells must acquire metabolic adaptations to fuel neoplastic progression. Mutations or changes in metabolic gene expression can impose nutrient dependencies in tumors, and even in the absence of metabolic defects, cancer cells can become...

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Bibliographic Details
Published in:Neuro Oncol
Main Authors: Minami, Jenna, Bayley, Nicholas, Tse, Christopher, Zhu, Henan, Morrow, Danielle, Yong, William, Liau, Linda, Cloughesy, Timothy, Graeber, Thomas, Nathanson, David
Format: Artigo
Language:Inglês
Published: Oxford University Press 2020
Subjects:
Tumor Microenvironment/Angiogenesis/Metabolism/Invasion
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651501/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.895
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