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TMOD-03. GLIOMAPDOX: A MOLECULARLY DIVERSE LIBRARY OF DIRECT-FROM-PATIENT ORTHOTOPIC GLIOMA XENOGRAFTS RECAPITULATES INTRATUMOR HETEROGENEITY
The development of effective treatments for malignant brain tumors has been hampered by the lack of robust preclinical models that faithfully capture the high inter- and intra-tumor heterogeneity of the human disease. Conventional cell lines lose the most common genetic abnormalities of glioblastoma...
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| Udgivet i: | Neuro Oncol |
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| Main Authors: | , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6217194/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.1116 |
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