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TMOD-03. GLIOMAPDOX: A MOLECULARLY DIVERSE LIBRARY OF DIRECT-FROM-PATIENT ORTHOTOPIC GLIOMA XENOGRAFTS RECAPITULATES INTRATUMOR HETEROGENEITY

The development of effective treatments for malignant brain tumors has been hampered by the lack of robust preclinical models that faithfully capture the high inter- and intra-tumor heterogeneity of the human disease. Conventional cell lines lose the most common genetic abnormalities of glioblastoma...

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Bibliografiske detaljer
Udgivet i:Neuro Oncol
Main Authors: Bayley, Nicholas, Baufeld, Lynn, Gosa, Laura, Morrow, Danielle, Tse, Christopher, Balanis, Nikolas, Yan, Weihong, Cloughesy, Timothy, Liau, Linda, Graeber, Thomas, Nathanson, David
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2018
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6217194/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.1116
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