IMMU-36. HIGH AFFINITY CHIMERIC ANTIGEN RECEPTOR WITH CROSS-REACTIVITY TO CLINICALLY-RELEVANT EGFR MUTATED PROTEINS

Tumor heterogeneity is one of the key reasons for therapeutic failure in Glioblastoma (GBM). Our chimeric antigen receptor (CAR) T cell clinical trial (NCT02209376) against Epidermal growth factor receptor (EGFR) variant III (EGFRvIII) demonstrated successful trafficking of T cells across the blood...

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Bibliographic Details
Published in:Neuro Oncol
Main Authors: Thokala, Radhika, Binder, Zev, Yin, Yibo, Milone, Michael, O’Rourke, Donald M
Format: Artigo
Language:Inglês
Published: Oxford University Press 2020
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7650978/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.466
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