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NIMG-47. METABOLIC CHARACTERIZATION OF IDH MUTANT LOWER GRADE GLIOMA USING SPECTROSCOPIC IMAGING OPTIMIZED FOR 2-HYDROXYGLUTARATE DETECTION

INTRODUCTION: Mutations in isocitrate dehydrogenase (IDH1/2) genes are both diagnostic and prognostic biomarkers for lower grade gliomas, which can be noninvasively evaluated via MRS detection of 2-hydroxyglutarate (2HG). A high percentage of lower grade gliomas harbor IDH mutations that have a majo...

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Publicat a:Neuro Oncol
Autors principals: LaFontaine, Marisa, Autry, Adam, Philips, Elizabeth, Jalbert, Llewellyn, Villanueva-Meyer, Javier, Chang, Susan, Li, Yan
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7650944/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.660
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