NIMG-47. METABOLIC CHARACTERIZATION OF IDH MUTANT LOWER GRADE GLIOMA USING SPECTROSCOPIC IMAGING OPTIMIZED FOR 2-HYDROXYGLUTARATE DETECTION

INTRODUCTION: Mutations in isocitrate dehydrogenase (IDH1/2) genes are both diagnostic and prognostic biomarkers for lower grade gliomas, which can be noninvasively evaluated via MRS detection of 2-hydroxyglutarate (2HG). A high percentage of lower grade gliomas harbor IDH mutations that have a majo...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Neuro Oncol
Prif Awduron: LaFontaine, Marisa, Autry, Adam, Philips, Elizabeth, Jalbert, Llewellyn, Villanueva-Meyer, Javier, Chang, Susan, Li, Yan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2020
Pynciau:
Neuroimaging
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7650944/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.660
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