CTNI-25. PHASE IB CLINICAL TRIAL OF CHRONIC CONVECTION-ENHANCED DELIVERY OF TOPOTECAN FOR RECURRENT GLIOBLASTOMA

OBJECTIVES: Convection-enhanced delivery (CED) provides pharmacokinetic advantages over systemic delivery for achieving cytotoxic drug levels into targeted regions of the brain. A major shortcoming of CED has been the need to limit treatment duration because of infection risks associated with extern...

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發表在:Neuro Oncol
Main Authors: Bruce, Jeffrey, Spinazzi, Eleonora, Lassman, Andrew, Iwamoto, Fabio, Welch, Mary, Banu, Matei, Argenziano, Michael, Upadhyayula, Pavan, Agar, Nathalie Y R, Humala, Nelson, Marie, Tamara, Pereira, Brianna, Sudhakar, Tejaswi, Mahajan, Aayushi, Neira, Justin, Lignelli-Dipple, Angela, Grinband, Jack, Sims, Peter, D’Amico, Randy, Canoll, Peter
格式: Artigo
語言:Inglês
出版: Oxford University Press 2020
主題:
Clinical Trials: Non-Immunologic
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7650341/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.192
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