Deconvolution of cell type-specific drug responses in human tumor tissue with single-cell RNA-seq

BACKGROUND: Preclinical studies require models that recapitulate the cellular diversity of human tumors and provide insight into the drug sensitivities of specific cellular populations. The ideal platform would enable rapid screening of cell type-specific drug sensitivities directly in patient tumor...

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Detalles Bibliográficos
Publicado en:Genome Med
Main Authors: Zhao, Wenting, Dovas, Athanassios, Spinazzi, Eleonora Francesca, Levitin, Hanna Mendes, Banu, Matei Alexandru, Upadhyayula, Pavan, Sudhakar, Tejaswi, Marie, Tamara, Otten, Marc L., Sisti, Michael B., Bruce, Jeffrey N., Canoll, Peter, Sims, Peter A.
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2021
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8114529/
https://ncbi.nlm.nih.gov/pubmed/33975634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-021-00894-y
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