Deconvolution of cell type-specific drug responses in human tumor tissue with single-cell RNA-seq

BACKGROUND: Preclinical studies require models that recapitulate the cellular diversity of human tumors and provide insight into the drug sensitivities of specific cellular populations. The ideal platform would enable rapid screening of cell type-specific drug sensitivities directly in patient tumor...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Genome Med
Egile Nagusiak: Zhao, Wenting, Dovas, Athanassios, Spinazzi, Eleonora Francesca, Levitin, Hanna Mendes, Banu, Matei Alexandru, Upadhyayula, Pavan, Sudhakar, Tejaswi, Marie, Tamara, Otten, Marc L., Sisti, Michael B., Bruce, Jeffrey N., Canoll, Peter, Sims, Peter A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2021
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8114529/
https://ncbi.nlm.nih.gov/pubmed/33975634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-021-00894-y
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