EPCO-11. IN VIVO FUNCTIONAL GENOMIC SCREEN IDENTIFIES WISP1 AS AN OVEREXPRESSED DRIVER OF GLIOBLASTOMA

There is a tremendous need to identify new genetic drivers of glioblastoma which can serve as potential therapeutic targets. In order to find new drivers, we leveraged genomic datasets to conduct a context specific in vivo functional genomic screen of overexpressed and/or amplified genes in GBM. We...

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Veröffentlicht in:Neuro Oncol
Hauptverfasser: Dasgupta, Pushan, Gumin, Joy, Pettazzoni, Piergiorgio, Barthel, Floris, Deem, Angela, Dey, Prasenjit, Huang-Hobbs, Emmet, Sulman, Erik, Verhaak, Roel, Lang, Frederick, Draetta, Giulio
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2020
Schlagworte:
(Epi)Genetics and Computational Omics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7650339/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.290
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