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HIV-cell membrane fusion intermediates are restricted by Serincs as revealed by cryo-electron and TIRF microscopy

To enter a cell and establish infection, HIV must first fuse its lipid envelope with the host cell plasma membrane. Whereas the process of HIV membrane fusion can be tracked by fluorescence microscopy, the 3D configuration of proteins and lipids at intermediate steps can only be resolved with cryo-e...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Ward, Amanda E., Kiessling, Volker, Pornillos, Owen, White, Judith M., Ganser-Pornillos, Barbie K., Tamm, Lukas K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7650252/
https://ncbi.nlm.nih.gov/pubmed/32788212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.014466
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