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Prefusion structure of syntaxin-1A suggests pathway for folding into neuronal trans-SNARE complex fusion intermediate

The assembly of the three neuronal soluble N-ethylmaleimide-sensitive factor attachment protein (SNAP) receptor (SNARE) proteins synaptobrevin 2, syntaxin-1A, and SNAP-25 is the key step that leads to exocytotic fusion of synaptic vesicles. In the fully assembled SNARE complex, these three proteins...

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Detalhes bibliográficos
Main Authors: Liang, Binyong, Kiessling, Volker, Tamm, Lukas K.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3845119/
https://ncbi.nlm.nih.gov/pubmed/24218570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1314699110
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