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Zymogen and activated protein C have similar structural architecture

Activated protein C is a trypsin-like protease with anticoagulant and cytoprotective properties that is generated by thrombin from the zymogen precursor protein C in a reaction greatly accelerated by the cofactor thrombomodulin. The molecular details of this activation remain elusive due to the lack...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Stojanovski, Bosko M., Pelc, Leslie A., Zuo, Xiaobing, Di Cera, Enrico
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7650249/
https://ncbi.nlm.nih.gov/pubmed/32855236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.014789
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