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Enhancing the anticoagulant profile of meizothrombin

Meizothrombin is an active intermediate generated during the proteolytic activation of prothrombin to thrombin in the penultimate step of the coagulation cascade. Structurally, meizothrombin differs from thrombin because it retains the auxiliary Gla domain and two kringles. Functionally, meizothromb...

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Détails bibliographiques
Publié dans:Biomol Concepts
Auteurs principaux: Stojanovski, Bosko M., Pelc, Leslie A., Zuo, Xiaobing, Pozzi, Nicola, Di Cera, Enrico
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6825329/
https://ncbi.nlm.nih.gov/pubmed/30864392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/bmc-2018-0016
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