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Convergent Synthesis of Sialyl Lewis(X)‑O‑Core‑1 Threonine

Selectins are a class of cell adhesion molecules that play a critical role during the initial steps of inflammation. The N-terminal domain of P-selectin glycoprotein ligand-1 (PSGL-1) binds to all selectins, but with the highest affinity to P-selectin. Recent evidence suggests that the blockade of P...

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Detalles Bibliográficos
Publicado en:J Org Chem
Main Authors: Sardar, Mohammed Y. R., Mandhapati, Appi Reddy, Park, Simon, Wever, Walter J., Cummings, Richard D., Chaikof, Elliot L.
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7648531/
https://ncbi.nlm.nih.gov/pubmed/29638128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.7b03117
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