Synthesis of Lewis(X)-O-Core-1 threonine: A building block for O-linked Lewis(X) glycopeptides

Lewis X (Le(X)) is a branched trisaccharide Galβ1→4(Fucα1→3)GlcNAc that is expressed on many cell surface glycoproteins and plays critical roles in innate and adaptive immune responses. However, efficient synthesis of glycopeptides bearing Le(X) remains a major limitation for structure-function stud...

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Publicado en:Carbohydr Res
Autores principales: Sardar, Mohammed Y. R., Krishnamurthy, Venkata R., Park, Simon, Mandhapati, Appi R., Wever, Walter J., Park, Dayoung, Cummings, Richard D., Chaikof, Elliot L.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5682196/
https://ncbi.nlm.nih.gov/pubmed/29065342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.carres.2017.10.002
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