Glycopeptide Analogues of PSGL-1 Inhibit P-Selectin In Vitro and In Vivo

Blockade of P-selectin/PSGL-1 interactions holds significant potential for treatment of disorders of innate immunity, thrombosis, and cancer. Current inhibitors remain limited due to low binding affinity or by the recognized disadvantages inherent to chronic administration of antibody therapeutics....

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Krishnamurthy, Venkata R, Sardar, Mohammed Y. R., Yu, Ying, Song, Xuezheng, Haller, Carolyn, Dai, Erbin, Wang, Xiacong, Hanjaya-Putra, Donny, Sun, Lijun, Morikis, Vasilios, Simon, Scott I., Woods, Robert, Cummings, Richard D., Chaikof, Elliot L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4423566/
https://ncbi.nlm.nih.gov/pubmed/25824568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7387
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