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Glycopeptide Analogues of PSGL-1 Inhibit P-Selectin In Vitro and In Vivo

Blockade of P-selectin/PSGL-1 interactions holds significant potential for treatment of disorders of innate immunity, thrombosis, and cancer. Current inhibitors remain limited due to low binding affinity or by the recognized disadvantages inherent to chronic administration of antibody therapeutics....

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Bibliografski detalji
Izdano u:Nat Commun
Glavni autori: Krishnamurthy, Venkata R, Sardar, Mohammed Y. R., Yu, Ying, Song, Xuezheng, Haller, Carolyn, Dai, Erbin, Wang, Xiacong, Hanjaya-Putra, Donny, Sun, Lijun, Morikis, Vasilios, Simon, Scott I., Woods, Robert, Cummings, Richard D., Chaikof, Elliot L.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4423566/
https://ncbi.nlm.nih.gov/pubmed/25824568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7387
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