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Chemoenzymatic synthesis of the sialyl Lewis X glycan and its derivatives
A combination of recombinant FKP and α-(1→3)-fucosyltransferase allows the facile synthesis of the sialyl Lewis X tetrasaccharide glycan and its derivatives in excellent yield. In this system, the universal fucosyl donor, guanidine 5′-diphosphate-β-L-fucose (GDP-fucose), or its analogues can be gene...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2945603/ https://ncbi.nlm.nih.gov/pubmed/20435300 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.carres.2010.03.032 |
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