Chemoenzymatic synthesis of GDP-l-fucose and the Lewis X glycan derivatives

Lewis X (Le(x))-containing glycans play important roles in numerous cellular processes. However, the absence of robust, facile, and cost-effective methods for the synthesis of Le(x) and its structurally related analogs has severely hampered the elucidation of the specific functions of these glycan e...

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Bibliografiska uppgifter
Huvudupphovsmän: Wang, Wei, Hu, Tianshun, Frantom, Patrick A., Zheng, Tianqing, Gerwe, Brian, del Amo, David Soriano, Garret, Sarah, Seidel, Ronald D., Wu, Peng
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2009
Ämnen:
Physical Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752511/
https://ncbi.nlm.nih.gov/pubmed/19805264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0908248106
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