Genomic Alterations of NTRK, POLE, ERBB2, and Microsatellite Instability Status in Chinese Patients with Colorectal Cancer

BACKGROUND: The increasing molecular characterization of colorectal cancers (CRCs) has spurred the need to look beyond RAS, BRAF, and microsatellite instability (MSI). Genomic alterations, including ERBB2 amplifications and mutations, POLE mutations, MSI, and NTRK1–3 fusions, have emerged as targets...

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Dettagli Bibliografici
Pubblicato in:Oncologist
Autori principali: Guo, Yun, Guo, Xian‐ling, Wang, Shuang, Chen, Xinyu, Shi, Jiaochun, Wang, Jian, Wang, Kai, Klempner, Samuel J., Wang, Weifeng, Xiao, Min
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley & Sons, Inc. 2020
Soggetti:
Cancer Diagnostics and Molecular Pathology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7648350/
https://ncbi.nlm.nih.gov/pubmed/32627883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2020-0356
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