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Identification and utilization of copy number information for correcting Hi-C contact map of cancer cell lines

BACKGROUND: Hi-C and its variant techniques have been developed to capture the spatial organization of chromatin. Normalization of Hi-C contact map is essential for accurate modeling and interpretation of high-throughput chromatin conformation capture (3C) experiments. Hi-C correction tools were ori...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Khalil, Ahmed Ibrahim Samir, Muzaki, Siti Rawaidah Binte Mohammad, Chattopadhyay, Anupam, Sanyal, Amartya
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7648276/
https://ncbi.nlm.nih.gov/pubmed/33160308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-020-03832-8
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