HiNT: a computational method for detecting copy number variations and translocations from Hi-C data

The three-dimensional conformation of a genome can be profiled using Hi-C, a technique that combines chromatin conformation capture with high-throughput sequencing. However, structural variations often yield features that can be mistaken for chromosomal interactions. Here, we describe a computationa...

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Bibliografske podrobnosti
izdano v:Genome Biol
Main Authors: Wang, Su, Lee, Soohyun, Chu, Chong, Jain, Dhawal, Kerpedjiev, Peter, Nelson, Geoffrey M., Walsh, Jennifer M., Alver, Burak H., Park, Peter J.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2020
Teme:
Method
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7087379/
https://ncbi.nlm.nih.gov/pubmed/32293513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-020-01986-5
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