Hi-C as a tool for precise detection and characterisation of chromosomal rearrangements and copy number variation in human tumours

Chromosomal rearrangements occur constitutionally in the general population and somatically in the majority of cancers. Detection of balanced rearrangements, such as reciprocal translocations and inversions, is troublesome, which is particularly detrimental in oncology where rearrangements play diag...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Genome Biol
Main Authors: Harewood, Louise, Kishore, Kamal, Eldridge, Matthew D., Wingett, Steven, Pearson, Danita, Schoenfelder, Stefan, Collins, V. Peter, Fraser, Peter
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2017
Teme:
Method
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5488307/
https://ncbi.nlm.nih.gov/pubmed/28655341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-017-1253-8
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