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Hi-C as a tool for precise detection and characterisation of chromosomal rearrangements and copy number variation in human tumours

Chromosomal rearrangements occur constitutionally in the general population and somatically in the majority of cancers. Detection of balanced rearrangements, such as reciprocal translocations and inversions, is troublesome, which is particularly detrimental in oncology where rearrangements play diag...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Harewood, Louise, Kishore, Kamal, Eldridge, Matthew D., Wingett, Steven, Pearson, Danita, Schoenfelder, Stefan, Collins, V. Peter, Fraser, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5488307/
https://ncbi.nlm.nih.gov/pubmed/28655341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-017-1253-8
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