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Hierarchical discovery of large-scale and focal copy number alterations in low-coverage cancer genomes
BACKGROUND: Detection of DNA copy number alterations (CNAs) is critical to understand genetic diversity, genome evolution and pathological conditions such as cancer. Cancer genomes are plagued with widespread multi-level structural aberrations of chromosomes that pose challenges to discover CNAs of...
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| Veröffentlicht in: | BMC Bioinformatics |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7160937/ https://ncbi.nlm.nih.gov/pubmed/32299346 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-020-3480-3 |
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