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Female sex mitigates motor and behavioural phenotypes in TDP-43(Q331K) knock-in mice
Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are overlapping neurodegenerative disorders. ALS is more commonly seen in men than women and the same may be the case for FTD. Preclinical models demonstrating sex-specific vulnerability may help to understand female resistance to...
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| 發表在: | Sci Rep |
|---|---|
| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group UK
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7645778/ https://ncbi.nlm.nih.gov/pubmed/33154447 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-76070-w |
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