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Female sex mitigates motor and behavioural phenotypes in TDP-43(Q331K) knock-in mice
Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are overlapping neurodegenerative disorders. ALS is more commonly seen in men than women and the same may be the case for FTD. Preclinical models demonstrating sex-specific vulnerability may help to understand female resistance to...
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| 出版年: | Sci Rep |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7645778/ https://ncbi.nlm.nih.gov/pubmed/33154447 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-76070-w |
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