The bone marrow microenvironment of pre-B acute lymphoblastic leukemia at single-cell resolution

The bone marrow microenvironment (BMM) plays a key role in leukemia progression, but its molecular complexity in pre-B cell acute lymphoblastic leukemia (B-ALL), the most common cancer in children, remains poorly understood. To gain further insight, we used single-cell RNA sequencing to characterize...

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Udgivet i:Sci Rep
Main Authors: Anderson, Denise, Skut, Patrycja, Hughes, Anastasia M., Ferrari, Emanuela, Tickner, Jennifer, Xu, Jiake, Mullin, Benjamin H., Tang, Dave, Malinge, Sébastien, Kees, Ursula R., Kotecha, Rishi S., Lassmann, Timo, Cheung, Laurence C.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7645756/
https://ncbi.nlm.nih.gov/pubmed/33154494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-76157-4
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