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A regulatory region on RIPK2 is required for XIAP binding and NOD signaling activity
Signaling via the intracellular pathogen receptors nucleotide‐binding oligomerization domain‐containing proteins NOD1 and NOD2 requires receptor interacting kinase 2 (RIPK2), an adaptor kinase that can be targeted for the treatment of various inflammatory diseases. However, the molecular mechanisms...
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| Publicado no: | EMBO Rep |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7645253/ https://ncbi.nlm.nih.gov/pubmed/32954645 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.202050400 |
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