A regulatory region on RIPK2 is required for XIAP binding and NOD signaling activity

Signaling via the intracellular pathogen receptors nucleotide‐binding oligomerization domain‐containing proteins NOD1 and NOD2 requires receptor interacting kinase 2 (RIPK2), an adaptor kinase that can be targeted for the treatment of various inflammatory diseases. However, the molecular mechanisms...

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Dades bibliogràfiques
Publicat a:EMBO Rep
Autors principals: Heim, Valentin J, Dagley, Laura F, Stafford, Che A, Hansen, Fynn M, Clayer, Elise, Bankovacki, Aleksandra, Webb, Andrew I, Lucet, Isabelle S, Silke, John, Nachbur, Ueli
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2020
Matèries:
Reports
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7645253/
https://ncbi.nlm.nih.gov/pubmed/32954645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.202050400
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