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Pyruvate Kinase M2 Coordinates Metabolism Switch between Glycolysis and Glutaminolysis in Cancer Cells

Cancer cells alter their nutrition metabolism to cope the stressful environment. One important metabolism adjustment is that cancer cells activate glutaminolysis in response to the reduced carbon from glucose entering into the TCA cycle due to inactivation of several enzymes in glycolysis. An import...

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Bibliografiske detaljer
Udgivet i:iScience
Main Authors: Li, Liangwei, Peng, Guangda, Liu, Xiaowei, Zhang, Yinwei, Han, Hongwei, Liu, Zhi-Ren
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7644948/
https://ncbi.nlm.nih.gov/pubmed/33196019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101684
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