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Pyruvate Kinase M2 Regulates Gene Transcription by Acting as A Protein Kinase
Pyruvate kinase isoform M2 (PKM2) is a glycolysis enzyme catalyzing conversion of phosphoenolpyruvate (PEP) to pyruvate with transferring a phosphate from PEP to ADP. We report here that PKM2 localizes to the cell nucleus. The levels of nuclear PKM2 correlate with cell proliferation. PKM2 activates...
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| Hoofdauteurs: | , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2012
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3299833/ https://ncbi.nlm.nih.gov/pubmed/22306293 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.01.001 |
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