Pyruvate Kinase M2 Regulates Gene Transcription by Acting as A Protein Kinase

Pyruvate kinase isoform M2 (PKM2) is a glycolysis enzyme catalyzing conversion of phosphoenolpyruvate (PEP) to pyruvate with transferring a phosphate from PEP to ADP. We report here that PKM2 localizes to the cell nucleus. The levels of nuclear PKM2 correlate with cell proliferation. PKM2 activates...

Full description

Saved in:

Bibliographic Details
Main Authors:	Gao, Xueliang, Wang, Haizhen, Jenny, J. Yang, Liu, Xiaowei, Liu, Zhi-Ren
Format:	Artigo
Language:	Inglês
Published:	2012
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3299833/ https://ncbi.nlm.nih.gov/pubmed/22306293 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.01.001
Tags:	Add Tag No Tags, Be the first to tag this record!

Pyruvate Kinase M2 Regulates Gene Transcription by Acting as A Protein Kinase

Similar Items