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Regulation and function of pyruvate kinase M2 in cancer
Altered metabolism is fundamental to the growth and survival of cancer cells. Pyruvate kinase M2 (PKM2), a key enzyme in cancer metabolism, has been demonstrated to play a central role not only in metabolic reprogramming but also in direct regulation of gene expression and subsequent cell cycle prog...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3950276/ https://ncbi.nlm.nih.gov/pubmed/23791887 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2013.06.008 |
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