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Protein kinase function of pyruvate kinase M2 and cancer

Pyruvate kinase is a terminal enzyme in the glycolytic pathway, where it catalyzes the conversion of phosphoenolpyruvate to pyruvate and production of ATP via substrate level phosphorylation. PKM2 is one of four isoforms of pyruvate kinase and is widely expressed in many types of tumors and associat...

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Detalhes bibliográficos
Publicado no:Cancer Cell Int
Main Authors: Chen, Xun, Chen, Shangwu, Yu, Dongsheng
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7597019/
https://ncbi.nlm.nih.gov/pubmed/33292198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-020-01612-1
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