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Pyruvate Kinase M2 Coordinates Metabolism Switch between Glycolysis and Glutaminolysis in Cancer Cells

Cancer cells alter their nutrition metabolism to cope the stressful environment. One important metabolism adjustment is that cancer cells activate glutaminolysis in response to the reduced carbon from glucose entering into the TCA cycle due to inactivation of several enzymes in glycolysis. An import...

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Podrobná bibliografie
Vydáno v:iScience
Hlavní autoři: Li, Liangwei, Peng, Guangda, Liu, Xiaowei, Zhang, Yinwei, Han, Hongwei, Liu, Zhi-Ren
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7644948/
https://ncbi.nlm.nih.gov/pubmed/33196019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101684
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