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SOCS, Intrinsic Virulence Factors, and Treatment of COVID-19

The suppressor of cytokine signaling (SOCS) family of intracellular checkpoint inhibitors has received little recognition compared to other checkpoint inhibitors. Two members of this family, SOCS1 and SOCS3, are indispensable, since SOCS1 knockout in mice results in neonatal death due to interferon...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Front Immunol
Hauptverfasser: Johnson, Howard M., Lewin, Alfred S., Ahmed, Chulbul M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7644869/
https://ncbi.nlm.nih.gov/pubmed/33193390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.582102
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