A cell penetrating peptide from SOCS-1 prevents ocular damage in experimental autoimmune uveitis

We describe an immunosuppressive peptide corresponding to the kinase inhibitory region (KIR) of the intracellular checkpoint protein suppressor of cytokine signaling 1 (SOCS-1) that binds to the phospho-tyrosine containing regions of the tyrosine kinases JAK2 and TYK2 and the adaptor protein MAL, an...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Exp Eye Res
Main Authors: Ahmed, Chulbul M., Massengill, Michael T., Brown, Emily E., Ildefonso, Cristhian J., Johnson, Howard M., Lewin, Alfred S.
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6528831/
https://ncbi.nlm.nih.gov/pubmed/30048621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2018.07.020
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